For Research Purposes Only — Not intended for human consumption or therapeutic use
The Copper Peptide
That Rebuilds
Your Skin
GHK-Cu (Glycyl-L-histidyl-L-lysine copper complex) activates over 4,000 skin genes. It is the only compound that simultaneously stimulates new collagen, breaks down damaged fibers, and restores the skin density lost through hormonal aging.
4,000+
Genes Activated
Including collagen & elastin
99.3%
HPLC Purity
3rd Party Verified
$69.99
Per 50mg Vial
Injectable + topical use
Copper peptide complex · ISO/IEC 17025 certified · Injectable & topical available
The Copper Complex Is
The Science Working
GHK-Cu is not just another skincare peptide — it is a naturally occurring copper complex found in human plasma, saliva, and urine. The copper ion is what gives GHK-Cu its remarkable biological power, enabling it to modulate enzyme activity, activate the LOX enzyme responsible for cross-linking collagen fibers, and function as a potent antioxidant within the dermal layer.
The copper(II) ion bound to the glycyl-L-histidyl-L-lysine tripeptide chain is what allows GHK-Cu to penetrate the dermal layer and signal skin cells directly. This copper-peptide bond is what separates GHK-Cu from simpler skincare peptides and explains why its results are structural — not just surface-level.
Rejuven GHK-Cu 50mg is tested for active copper content via ICP-MS spectrometry — a specialized test for metal quantification that less rigorous suppliers skip — ensuring every vial contains a fully active copper-peptide complex.
Copper Content Verified. Rejuven GHK-Cu is independently tested via ICP-MS copper quantification — confirming the active copper-peptide complex in every vial.
Four Ways GHK-Cu Transforms Skin
GHK-Cu doesn't just moisturize. It doesn't just plump. It fundamentally restructures the skin's biology — from the gene expression level up through visible surface appearance.
Collagen & Elastin Synthesis
GHK-Cu directly activates fibroblast cells — the factories responsible for producing collagen Types I, III, and IV as well as elastin. Studies show up to a 70% increase in skin collagen with consistent GHK-Cu use, restoring the structural scaffolding that makes skin appear firm, plump, and youthful.
- +70% collagen increase
- Types I, III & IV activated
- Fibroblast reactivation
Bidirectional Skin Remodeling
Unlike simple collagen creams that only add surface moisture, GHK-Cu performs a dual action: it breaks down old, damaged, cross-linked collagen fibers (which cause visible wrinkles and rough texture) while simultaneously building fresh, organized collagen. This remodeling — not just supplementing — is what creates lasting structural change.
- Degrades damaged collagen
- Builds organized new fibers
- Reduces deep line depth
Gene Expression Activation
GHK-Cu has been shown to modulate the expression of over 4,000 human genes — including antioxidant defense genes, anti-inflammatory pathways, DNA repair genes, and stem cell activation signals. This makes it far more than a topical cosmetic ingredient: it is a molecular signal that tells your skin to rejuvenate itself from within.
- 4,000+ genes modulated
- DNA repair pathways activated
- Stem cell signals restored
Hyaluronic Acid & Hydration
GHK-Cu stimulates glycosaminoglycan synthesis — including hyaluronic acid — which is responsible for skin's moisture-binding capacity and plumpness. As estrogen declines, hyaluronic acid production drops dramatically, leading to the hollow, deflated look women experience perimenopausal. GHK-Cu restores this independently of hormonal levels.
- ↑ HA synthesis
- Deeper hydration layers
- Plumpness restoration
GHK-Cu Declines 60% by Age 60
Your body produces GHK-Cu naturally — at its peak. At age 20, plasma GHK-Cu is approximately 200 ng/mL. By 60, it has dropped to ~80 ng/mL. That 60% decline directly maps onto the visible acceleration of skin aging. Supplementing restores the signaling your skin needs to keep regenerating.
Skin Transformations
Women across the country are using GHK-Cu to reclaim the skin density, firmness, and glow that hormonal changes took away.
Before: Post-menopausal skin thinning, significant collagen loss, deep forehead lines, sagging jawline. Skin felt paper-thin.
People stopped me at my daughter's wedding to ask if I'd had Botox. I haven't touched my face. After 10 weeks of GHK-Cu injections combined with the facial cream, my skin is dense and firm the way it felt in my 30s. The lines on my forehead are still there but they're soft — like they belong. My face looks like mine again.
Diana L., 56
Miami, FL
Visibly restored
Firmness
Softened 60–70%
Lines
Smooth & dense
Texture
Maria C., 44
Los Angeles, CASignificantly faded
Scarring
Restored
Plumpness
Radiant
Glow
“I started noticing my skin looked deflated — like the volume was just gone. After 8 weeks of GHK-Cu I look genuinely rested and firm. The acne scarring I've had for 15 years has visibly faded. I use both and together they work like nothing I've ever tried in 20 years of skincare.”
Injectable + Facial Cream
Rachel B., 49
New York, NYTightened
Laxity
Softened
Folds
↑ Visibly
Density
“I've spent thousands on professional facials and laser treatments. GHK-Cu did more for my skin's actual structure in 12 weeks than everything else combined. My dermatologist asked what I was doing because my skin looked denser on her handheld imaging tool.”
Injectable Protocol
Sophia T., 38
Chicago, ILEvened out
Tone
Restored
Glow
Smoothed
Lines
“I started the cream early because I could see my skin changing with my hormonal shifts. Six weeks in and I have the glow I thought I'd lost. My skin looks fresh and even — like I've been on vacation for a month. I'm never stopping.”
GHK-Cu Facial Cream
4.9 / 5
Average Rating
99.3%
HPLC Purity
8–12 wks
Avg. Visible Results
4,000+
Genes Activated
* Individual results vary. These testimonials represent personal experiences. Results achieved as part of a comprehensive skincare protocol. These statements have not been evaluated by the FDA.
Injectable + Topical — The Complete Protocol
GHK-Cu Injectable 50mg
Subcutaneous injection delivers GHK-Cu systemically — reaching the deep dermal layers where collagen-producing fibroblasts live. Also supports hair follicle health, anti-inflammation, and systemic tissue repair.
- 1Reconstitute with bacteriostatic water
- 2Inject 1–2mg subcutaneously daily or every other day
- 3Inject near face/neck or general subQ for systemic effect
- 4Store at 2–8°C after reconstitution
GHK-Cu Facial Cream
Our Signature Facial Cream delivers 0.5% active GHK-Cu complex directly to facial skin twice daily. Formulated with hyaluronic acid, niacinamide 5%, and vitamin C derivative for a complete anti-aging daily ritual.
- 1Apply pea-sized amount to clean dry skin
- 2Massage in upward circles morning and evening
- 3Follow with SPF in the morning
- 4Results visible in 4–6 weeks with consistent use
Best Results: Use Both Together
The injectable peptide delivers deep structural collagen remodeling. The facial cream maintains daily surface stimulation. Together they create a 24/7 skin renewal environment that neither achieves alone.
GHK-Cu FAQ
GHK-Cu is Glycyl-L-histidyl-L-lysine copper(II) complex — a naturally occurring tripeptide found in human plasma, saliva, and urine. The copper ion bonded to the peptide chain is what gives it its extraordinary biological power: it modulates enzyme activity, activates the LOX enzyme responsible for cross-linking collagen fibers, and functions as a potent antioxidant within the dermal layer. It is the most extensively studied copper-peptide complex in anti-aging science.
Ready to start your skin transformation?
Available as injectable peptide and daily facial cream.
Your Skin Can Look
Like This Again
99.3% purity. Copper content verified by ICP-MS. Designed for women's hormonal skin aging. Available as injectable peptide and daily facial cream.
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